Anti-Recombinant-TPM1 antibody [RM1M09] (STJA0023696)

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STJA0023696
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: FC/IF/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Tropomyosin Alpha-1 Chain is suitable for use in Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM1M09
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: FCM: 1:20-1:100
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: TPM1
Gene ID: 7168
Uniprot ID: TPM1_HUMAN
Post Translational Modifications Phosphorylated at Ser-283 by DAPK1 in response to oxidative stress and this phosphorylation enhances stress fiber formation in endothelial cells.
Function Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Protein Name Tropomyosin Alpha-1 Chain
Alpha-Tropomyosin
Tropomyosin-1
Database Links Reactome: R-HSA-390522
Reactome: R-HSA-445355
Cellular Localisation Cytoplasm
Cytoskeleton
Associates With F-Actin Stress Fibers
Alternative Antibody Names Anti-Tropomyosin Alpha-1 Chain antibody
Anti-Alpha-Tropomyosin antibody
Anti-Tropomyosin-1 antibody
Anti-TPM1 antibody
Anti-C15orf13 antibody
Anti-TMSA antibody

Information sourced from Uniprot.org

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