| Short Description : | Rabbit monoclonal anti-Recombinant-Serpin B3 for use in IF, IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IF/IHC/WB |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | RM1T76 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | IF: 1:50-1:200 |
| Formulation: | 0.01M PBS |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | SERPINB3 |
| Gene ID: | 6317 |
| Uniprot ID: | SPB3_HUMAN |
| Function | May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1). |
| Protein Name | Serpin B3Protein T4-ASquamous Cell Carcinoma Antigen 1Scca-1 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | CytoplasmSeems To Also Be Secreted In Plasma By Cancerous Cells But At A Low Level |
| Alternative Antibody Names | Anti-Serpin B3 antibodyAnti-Protein T4-A antibodyAnti-Squamous Cell Carcinoma Antigen 1 antibodyAnti-Scca-1 antibodyAnti-SERPINB3 antibodyAnti-SCCA antibodyAnti-SCCA1 antibody |
Information sourced from Uniprot.org
