Anti-Recombinant-SAE1 antibody [RM2N77] (STJA0026239)

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STJA0026239
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: IF/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Sumo-Activating Enzyme Subunit 1 is suitable for use in Immunofluorescence and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2N77
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IF: 1:50-1:200, WB: 1:500-1:1000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: SAE1
Gene ID: 10055
Uniprot ID: SAE1_HUMAN
Function The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Protein Name Sumo-Activating Enzyme Subunit 1
Ubiquitin-Like 1-Activating Enzyme E1a Cleaved Into - Sumo-Activating Enzyme Subunit 1 - N-Terminally Processed
Database Links Reactome: R-HSA-3065676
Reactome: R-HSA-3065678
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Sumo-Activating Enzyme Subunit 1 antibody
Anti-Ubiquitin-Like 1-Activating Enzyme E1a Cleaved Into - Sumo-Activating Enzyme Subunit 1 - N-Terminally Processed antibody
Anti-SAE1 antibody
Anti-AOS1 antibody
Anti-SUA1 antibody
Anti-UBLE1A antibody

Information sourced from Uniprot.org

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