Anti-Recombinant-PUS1 antibody [RM2S70] (STJA0026628)

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STJA0026628
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: IF/IP/WB
Reactivity: Human/Rat/Hamster
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Pseudouridylate Synthase 1 Homolog is suitable for use in Immunofluorescence, Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2S70
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IF: 1:50-1:200, IP: 1:20, WB: 1:500-1:1000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: PUS1
Gene ID: 80324
Uniprot ID: PUS1_HUMAN
Function Pseudouridylate synthase that catalyzes pseudouridylation of tRNAs and mRNAs. Acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3'. Acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions. Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing. Involved in regulation of nuclear receptor activity through pseudouridylation of SRA1 mRNA.
Protein Name Pseudouridylate Synthase 1 Homolog
Trna Pseudouridine Synthase 1
Trna Pseudouridine(38-40 Synthase
Trna Pseudouridylate Synthase I
Trna-Uridine Isomerase I
Database Links Reactome: R-HSA-6782315 Q9Y606-2
Reactome: R-HSA-6787450 Q9Y606-1
Cellular Localisation Isoform 1: Mitochondrion
Isoform 2: Nucleus
Cytoplasm
Alternative Antibody Names Anti-Pseudouridylate Synthase 1 Homolog antibody
Anti-Trna Pseudouridine Synthase 1 antibody
Anti-Trna Pseudouridine(38-40 Synthase antibody
Anti-Trna Pseudouridylate Synthase I antibody
Anti-Trna-Uridine Isomerase I antibody
Anti-PUS1 antibody
Anti-PP8985 antibody

Information sourced from Uniprot.org

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