Anti-Recombinant-PTPRR antibody [RM2G16] (STJA0025584)

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STJA0025584
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Short Description :Rabbit monoclonal anti-Recombinant-Receptor-Type Tyrosine-Protein Phosphatase R for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/WB
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :RM2G16
Isotype:IgG
Conjugation:Unconjugated
Purification:Protein A/G purified from cell culture supernatant
Dilution Range:IHC: 1:100-1:200, WB: 1:1000-1:2000
Formulation:0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol:PTPRR
Gene ID:5801
Uniprot ID:PTPRR_HUMAN
Function Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus.
Protein Name Receptor-Type Tyrosine-Protein Phosphatase R
R-Ptp-R
Ch-1ptpase
Nc-Ptpcom1
Protein-Tyrosine Phosphatase Pcptp1
Database Links
Cellular Localisation Secreted
Isoform Alpha: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform Delta: Cytoplasm
Perinuclear Region
Locates To The Perinuclear Areas Within The Cytoplasm
Isoform Gamma: Cytoplasm
Alternative Antibody Names Anti-Receptor-Type Tyrosine-Protein Phosphatase R antibody
Anti-R-Ptp-R antibody
Anti-Ch-1ptpase antibody
Anti-Nc-Ptpcom1 antibody
Anti-Protein-Tyrosine Phosphatase Pcptp1 antibody
Anti-PTPRR antibody
Anti-ECPTP antibody
Anti-PTPRQ antibody

Information sourced from Uniprot.org

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