Anti-Recombinant-PLEC/Plectin antibody [RM1A57] (STJA0026728)

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STJA0026728
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Host: Rabbit
Applications: IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Plectin is suitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM1A57
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: PLEC
Gene ID: 5339
Uniprot ID: PLEC_HUMAN
Post Translational Modifications Phosphorylated by CDK1.regulates dissociation from intermediate filaments during mitosis.
Function Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity.
Protein Name Plectin
Pcn
Pltn
Hemidesmosomal Protein 1
Hd1
Plectin-1
Database Links Reactome: R-HSA-2022090
Reactome: R-HSA-264870
Reactome: R-HSA-446107
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Junction
Hemidesmosome
Cell Projection
Podosome
Localized To The Cortex Of Myotube Podosomes
Alternative Antibody Names Anti-Plectin antibody
Anti-Pcn antibody
Anti-Pltn antibody
Anti-Hemidesmosomal Protein 1 antibody
Anti-Hd1 antibody
Anti-Plectin-1 antibody
Anti-PLEC antibody
Anti-PLEC1 antibody

Information sourced from Uniprot.org