Anti-Recombinant-PLAU/Urokinase antibody [RM1H42] (STJA0023333)

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STJA0023333
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Short Description :Rabbit monoclonal anti-Recombinant-Urokinase-Type Plasminogen Activator for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/WB
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :RM1H42
Isotype:IgG
Conjugation:Unconjugated
Purification:Protein A/G purified from cell culture supernatant
Dilution Range:IHC: 1:100-1:200
Formulation:0.01M PBS
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol:PLAU
Gene ID:5328
Uniprot ID:UROK_HUMAN
Post Translational Modifications Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding. Produced as an inactive single-chain protein (pro-uPA or sc-uPA), is processed into the active disulfide-linked two-chain form of PLAU/uPA by a proteolytic event mediated, at least, by TMPRSS4.
Function Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.
Protein Name Urokinase-Type Plasminogen Activator
U-Plasminogen Activator
Upa Cleaved Into - Urokinase-Type Plasminogen Activator Long Chain A - Urokinase-Type Plasminogen Activator Short Chain A - Urokinase-Type Plasminogen Activator Chain B
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-75205
Cellular Localisation Secreted
Alternative Antibody Names Anti-Urokinase-Type Plasminogen Activator antibody
Anti-U-Plasminogen Activator antibody
Anti-Upa Cleaved Into - Urokinase-Type Plasminogen Activator Long Chain A - Urokinase-Type Plasminogen Activator Short Chain A - Urokinase-Type Plasminogen Activator Chain B antibody
Anti-PLAU antibody

Information sourced from Uniprot.org

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