Anti-Recombinant-P4HTM antibody [RM2RM70] (STJA0026529)

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STJA0026529
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: FC/IHC/IP/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Transmembrane Prolyl 4-Hydroxylase is suitable for use in Flow Cytometry, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2RM70
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: FCM: 1:20-1:100, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: P4HTM
Gene ID: 54681
Uniprot ID: P4HTM_HUMAN
Post Translational Modifications Glycosylated.
Function Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
Protein Name Transmembrane Prolyl 4-Hydroxylase
P4h-Tm
Hypoxia-Inducible Factor Prolyl Hydroxylase 4
Hif-Ph4
Hif-Prolyl Hydroxylase 4
Hph-4
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Transmembrane Prolyl 4-Hydroxylase antibody
Anti-P4h-Tm antibody
Anti-Hypoxia-Inducible Factor Prolyl Hydroxylase 4 antibody
Anti-Hif-Ph4 antibody
Anti-Hif-Prolyl Hydroxylase 4 antibody
Anti-Hph-4 antibody
Anti-P4HTM antibody
Anti-PH4 antibody

Information sourced from Uniprot.org

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