| Host: |
Mouse |
| Applications: |
WB/IHC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Recombinant-non-muscle Myosin IIB/MYH10 is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
SM0587 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1k |
| Formulation: |
PBS with 0.15% ProClin300, 100 Mu g/mL BSA and 50% glycerol. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB (H, M, R) 1:500-1:1000IHC/IF (H, M, R) 1:250-1:1000 |
| Storage Instruction: |
Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: |
Myh10 |
| Gene ID: |
77579 |
| Uniprot ID: |
MYH10_MOUSE |
| Immunogen: |
KLHconjugatedSyntheticpeptidecorrespondingtoMouseMYH10 |
| Post Translational Modifications | Phosphorylated by ABL2. |
| Function | Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension.this function is mechanically antagonized by MYH9. Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. |
| Protein Name | Myosin-10Cellular Myosin Heavy Chain - Type BMyosin Heavy Chain 10Myosin Heavy Chain - Non-Muscle IibNon-Muscle Myosin Heavy Chain BNmmhc-BNon-Muscle Myosin Heavy Chain IibNmmhc Ii-BNmmhc-Iib |
| Database Links | Reactome: R-MMU-5627123 |
| Cellular Localisation | Cell ProjectionLamellipodiumColocalizes With Mcc At The Leading Edge Of Migrating Cells |
| Alternative Antibody Names | Anti-Myosin-10 antibodyAnti-Cellular Myosin Heavy Chain - Type B antibodyAnti-Myosin Heavy Chain 10 antibodyAnti-Myosin Heavy Chain - Non-Muscle Iib antibodyAnti-Non-Muscle Myosin Heavy Chain B antibodyAnti-Nmmhc-B antibodyAnti-Non-Muscle Myosin Heavy Chain Iib antibodyAnti-Nmmhc Ii-B antibodyAnti-Nmmhc-Iib antibodyAnti-Myh10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
