| Short Description : | Rabbit monoclonal anti-Recombinant-Cytoplasmic Protein Nck2 for use in IF and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IF/WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | RM1E24 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | IF: 1:50-1:200 |
| Formulation: | 0.01M PBS |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Post Translational Modifications | Phosphorylated. |
| Function | Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. |
| Protein Name | Cytoplasmic Protein Nck2Growth Factor Receptor-Bound Protein 4Nck Adaptor Protein 2Nck-2Sh2/Sh3 Adaptor Protein Nck-Beta |
| Database Links | Reactome: R-HSA-186763Reactome: R-HSA-373753Reactome: R-HSA-3928664Reactome: R-HSA-428540Reactome: R-HSA-4420097Reactome: R-HSA-8985801Reactome: R-HSA-9013420Reactome: R-HSA-9013424 |
| Cellular Localisation | CytoplasmEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Cytoplasmic Protein Nck2 antibodyAnti-Growth Factor Receptor-Bound Protein 4 antibodyAnti-Nck Adaptor Protein 2 antibodyAnti-Nck-2 antibodyAnti-Sh2/Sh3 Adaptor Protein Nck-Beta antibodyAnti-NCK2 antibodyAnti-GRB4 antibody |
Information sourced from Uniprot.org
