Anti-Recombinant-MYH10 antibody [RM1V13] (STJA0024492)

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STJA0024492
£309.50 - £472.50
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Host: Rabbit
Applications: IP/WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Myosin-10 is suitable for use in Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM1V13
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IP: 1:20
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: MYH10
Gene ID: 4628
Uniprot ID: MYH10_HUMAN
Post Translational Modifications Phosphorylated by ABL2.
Function Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension.this function is mechanically antagonized by MYH9. (Microbial infection) Acts as a receptor for herpes simplex virus 1/HHV-1 envelope glycoprotein B.
Protein Name Myosin-10
Cellular Myosin Heavy Chain - Type B
Myosin Heavy Chain 10
Myosin Heavy Chain - Non-Muscle Iib
Non-Muscle Myosin Heavy Chain B
Nmmhc-B
Non-Muscle Myosin Heavy Chain Iib
Nmmhc Ii-B
Nmmhc-Iib
Database Links Reactome: R-HSA-3928663
Reactome: R-HSA-416572
Reactome: R-HSA-5625740
Reactome: R-HSA-5625900
Reactome: R-HSA-5627117
Reactome: R-HSA-5627123
Cellular Localisation Cell Projection
Lamellipodium
Colocalizes With Mcc At The Leading Edge Of Migrating Cells
Cell Membrane
(Microbial Infection) Localizes At The Surface Of The Cell Membrane Following Infection By Herpes Simplex Virus 1/Hhv-1
Alternative Antibody Names Anti-Myosin-10 antibody
Anti-Cellular Myosin Heavy Chain - Type B antibody
Anti-Myosin Heavy Chain 10 antibody
Anti-Myosin Heavy Chain - Non-Muscle Iib antibody
Anti-Non-Muscle Myosin Heavy Chain B antibody
Anti-Nmmhc-B antibody
Anti-Non-Muscle Myosin Heavy Chain Iib antibody
Anti-Nmmhc Ii-B antibody
Anti-Nmmhc-Iib antibody
Anti-MYH10 antibody

Information sourced from Uniprot.org