Anti-Recombinant-MYBBP1A antibody [RM2P45] (STJA0026306)

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STJA0026306
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: FC/IF/IHC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Myb-Binding Protein 1a is suitable for use in Flow Cytometry, Immunofluorescence, Immunohistochemistry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2P45
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: MYBBP1A
Gene ID: 10514
Uniprot ID: MBB1A_HUMAN
Function May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter. Has a role in rRNA biogenesis together with PWP1.
Protein Name Myb-Binding Protein 1a
Database Links Reactome: R-HSA-5250924
Cellular Localisation Cytoplasm
Nucleus
Nucleolus
Shuttles Between The Nucleus And Cytoplasm
Nuclear Import May Be Mediated By Kpna2
While Export Appears To Depend Partially On Xpo1/Crm1
Predominantly Nucleolar
Alternative Antibody Names Anti-Myb-Binding Protein 1a antibody
Anti-MYBBP1A antibody
Anti-P160 antibody

Information sourced from Uniprot.org

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