Anti-Recombinant-MAGEC2 antibody [RM2M65] (STJA0026128)

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STJA0026128
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Host: Rabbit
Applications: IHC/IP/WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Melanoma-Associated antigen C2 is suitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2M65
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: MAGEC2
Gene ID: 51438
Uniprot ID: MAGC2_HUMAN
Function Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.
Protein Name Melanoma-Associated Antigen C2
Cancer/Testis Antigen 10
Ct10
Hepatocellular Carcinoma-Associated Antigen 587
Mage-C2 Antigen
Mage-E1 Antigen
Cellular Localisation Cytoplasm
Nucleus
Nuclear In Germ Cells
Cytoplasmic In Well-Differentiated Hepatocellular Carcinoma
Nuclear In Moderately- And Poorly-Differentiated Hepatocellular Carcinoma
Alternative Antibody Names Anti-Melanoma-Associated Antigen C2 antibody
Anti-Cancer/Testis Antigen 10 antibody
Anti-Ct10 antibody
Anti-Hepatocellular Carcinoma-Associated Antigen 587 antibody
Anti-Mage-C2 Antigen antibody
Anti-Mage-E1 Antigen antibody
Anti-MAGEC2 antibody
Anti-HCA587 antibody
Anti-MAGEE1 antibody

Information sourced from Uniprot.org

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