| Host: | Rabbit |
| Applications: | FC/IHC/WB |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal antibody anti-Recombinant-Involucrin is suitable for use in Flow Cytometry, Immunohistochemistry and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | RM1L10 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.01M PBS |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | FCM: 1:20-1:100 |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | IVL |
| Gene ID: | 3713 |
| Uniprot ID: | INVO_HUMAN |
| Post Translational Modifications | Substrate of transglutaminase. Some glutamines and lysines are cross-linked to other involucrin molecules, to other proteins such as keratin, desmoplakin, periplakin and envoplakin, and to lipids like omega-hydroxyceramide. |
| Function | Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. |
| Protein Name | Involucrin |
| Database Links | Reactome: R-HSA-6809371Reactome: R-HSA-9725554 |
| Cellular Localisation | CytoplasmConstituent Of The Scaffolding Of The Cornified Envelope |
| Alternative Antibody Names | Anti-Involucrin antibodyAnti-IVL antibody |
Information sourced from Uniprot.org
