Anti-Recombinant-IRF6 antibody [RM1D35] (STJA0022930)

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STJA0022930
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Short Description :Rabbit monoclonal anti-Recombinant-Interferon Regulatory Factor 6 for use in IF, IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IF/IHC/WB
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :RM1D35
Isotype:IgG
Conjugation:Unconjugated
Purification:Protein A/G purified from cell culture supernatant
Dilution Range:IF: 1:50-1:200
Formulation:0.01M PBS
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol:IRF6
Gene ID:3664
Uniprot ID:IRF6_HUMAN
Post Translational Modifications Phosphorylated. Phosphorylation status depends on the cell cycle and is a signal for ubiquitination and proteasome-mediated degradation.
Function Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development. Plays a role in regulating mammary epithelial cell proliferation. May regulate WDR65 transcription.
Protein Name Interferon Regulatory Factor 6
Irf-6
Database Links Reactome: R-HSA-877300
Reactome: R-HSA-909733
Cellular Localisation Nucleus
Cytoplasm
Translocates To Nucleus In Response To An Activating Signal
Alternative Antibody Names Anti-Interferon Regulatory Factor 6 antibody
Anti-Irf-6 antibody
Anti-IRF6 antibody

Information sourced from Uniprot.org

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