Anti-Recombinant-EPS15L1/EPS15R antibody [RM2S45] (STJA0026603)

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STJA0026603
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: IP/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Epidermal Growth Factor Receptor Substrate 15-Like 1 is suitable for use in Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2S45
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IP: 1:20, WB: 1:500-1:1000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: EPS15L1
Gene ID: 58513
Uniprot ID: EP15R_HUMAN
Function Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR).internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.
Protein Name Epidermal Growth Factor Receptor Substrate 15-Like 1
Eps15-Related Protein
Eps15r
Database Links Reactome: R-HSA-182971
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Nucleus
Membrane
Coated Pit
Localized To Plasma Membrane Coated Pits
Alternative Antibody Names Anti-Epidermal Growth Factor Receptor Substrate 15-Like 1 antibody
Anti-Eps15-Related Protein antibody
Anti-Eps15r antibody
Anti-EPS15L1 antibody
Anti-EPS15R antibody

Information sourced from Uniprot.org

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