| Short Description : | Rabbit monoclonal anti-Recombinant-Coilin for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | RM1V51 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | WB: 1:500-1:1000 |
| Formulation: | 0.01M PBS |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | COIL |
| Gene ID: | 8161 |
| Uniprot ID: | COIL_HUMAN |
| Post Translational Modifications | Symmetrical dimethylation of arginine residues within the RG repeat region enhances affinity for SMN, and thus localization of SMN complexes to CBs. Phosphorylated by VRK1. Phosphorylation during mitosis is associated with disassembly of CBs. |
| Function | Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs. |
| Protein Name | CoilinP80-Coilin |
| Database Links | |
| Cellular Localisation | NucleusCajal Body |
| Alternative Antibody Names | Anti-Coilin antibodyAnti-P80-Coilin antibodyAnti-COIL antibodyAnti-CLN80 antibody |
Information sourced from Uniprot.org
