| Host: |
Rabbit |
| Applications: |
IP/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Rabbit monoclonal anti-Recombinant-M-Phase Inducer Phosphatase 2 for use in IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : |
Monoclonal |
| Clone ID : |
RM1T94 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.01M PBS |
| Purification: |
Protein A/G purified from cell culture supernatant |
| Dilution Range: |
IP: 1:20-1:50 |
| Storage Instruction: |
Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Function | Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. The three isoforms seem to have a different level of activity. |
| Protein Name | M-Phase Inducer Phosphatase 2Dual Specificity Phosphatase Cdc25b |
| Database Links | Reactome: R-HSA-69273Reactome: R-HSA-69656Reactome: R-HSA-8862803Reactome: R-HSA-9825892 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindle Pole |
| Alternative Antibody Names | Anti-M-Phase Inducer Phosphatase 2 antibodyAnti-Dual Specificity Phosphatase Cdc25b antibodyAnti-CDC25B antibodyAnti-CDC25HU2 antibody |
Information sourced from Uniprot.org
