Anti-Recombinant-CBS antibody [RM1V05] (STJA0024484)

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STJA0024484
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Short Description :Rabbit monoclonal anti-Recombinant-Cystathionine Beta-Synthase for use in IF, IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IF/IHC/WB
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :RM1V05
Isotype:IgG
Conjugation:Unconjugated
Purification:Protein A/G purified from cell culture supernatant
Dilution Range:IF: 1:50-1:200
Formulation:0.01M PBS
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol:CBS
Gene ID:102724560/875
Uniprot ID:CBS_HUMAN
Function Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons.
Protein Name Cystathionine Beta-Synthase
Beta-Thionase
Serine Sulfhydrase
Database Links Reactome: R-HSA-1614603
Reactome: R-HSA-2408508
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Cystathionine Beta-Synthase antibody
Anti-Beta-Thionase antibody
Anti-Serine Sulfhydrase antibody
Anti-CBS antibody

Information sourced from Uniprot.org