Anti-RDM1 antibody (125-284) (STJ28927)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RDM1 (125-284) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RDM1 |
| Gene ID | 201299 |
| Uniprot ID | RDM1_HUMAN |
| Immunogen Region | 125-284 |
| Immunogen Sequence | NGCSKRIIKLQELSDLEERE NEDSMVPLPKQSLKFFCALE VVLPSCDCRSPGIGLVEEPM DKVEEGPLSFLMKRKTAQKL AIQKALSDAFQKLLIVVLES GKIAVEYRPSEDIVGVRCEE ELHGLIQVPCSPWKQYGQEE EGYLSDFSLEEEEFRLPELD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 125-284 of human RDM1 (NP_663629.1). |
Additional Info
| Tissue Specificity | Expressed in testis. |
| Function | May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA. |
| Protein Name | Rad52 Motif-Containing Protein 1Rad52 Homolog B |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmNucleolusIsoform 3 And Isoform 10 Are Predominantly Nuclear And NucleolarAfter Treatment With Proteasomal Inhibitors And Mild Heat-Shock StressIsoform 1Isoform 3Isoform 5Isoform 7Isoform 8 And Isoform 10 Are Relocalized To The Nucleolus As Dot-Like Or Irregular Subnuclear StructuresIsoform 1 Colocalized With Nuclear Promyelocytic Leukemia (Pml) And Cajal Bodies (Cb)This Association With Nuclear Bodies Is Enhanced In Response To Proteotoxic StressBut Not Isoform 1 And Isoform 5Is Relocalized In Nucleolar Caps During Transcriptional ArrestIsoform 1: CytoplasmPml BodyCajal BodyIsoform 1 Is Predominantly Cytoplasmic |
| Alternative Antibody Names | Anti-Rad52 Motif-Containing Protein 1 antibodyAnti-Rad52 Homolog B antibodyAnti-RDM1 antibodyAnti-RAD52B antibody |
Information sourced from Uniprot.org