| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RBM11 (1-281) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RBM11 |
| Gene ID: |
54033 |
| Uniprot ID: |
RBM11_HUMAN |
| Immunogen Region: |
1-281 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-281 of human RBM11 (NP_658983.3). |
| Immunogen Sequence: |
MFPAQEEADRTVFVGNLEAR VREEILYELFLQAGPLTKVT ICKDREGKPKSFGFVCFKHP ESVSYAIALLNGIRLYGRPI NVQYRFGSSRSSEPANQSFE SCVKINSHNYRNEEMLVGRS SFPMQYFPINNTSLPQEYFL FQKMQWHVYNPVLQLPYYEM TAPLPNSASVSSSLNHVPDL EAGPSSYKWTHQQPSDSDLY QMTAPLPNSASVSSSLNHVP DLEAGPSSYKWTHQQPSDS |
| Tissue Specificity | Expressed in brain, hippocampus, prefrontal cortex, cerebellum, spinal cord, testis, mammary gland, spleen and kidney. Also expressed in fetal brain. |
| Function | Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1. |
| Protein Name | Splicing Regulator Rbm11Rna-Binding Motif Protein 11 |
| Cellular Localisation | NucleusNucleoplasmNucleus SpeckleEnriched In Srsf2-Containing Splicing SpecklesShuttles Between Nucleoplasm And Speckles |
| Alternative Antibody Names | Anti-Splicing Regulator Rbm11 antibodyAnti-Rna-Binding Motif Protein 11 antibodyAnti-RBM11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
