| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RBFOX1 |
| Gene ID: | 54715 |
| Uniprot ID: | RFOX1_HUMAN |
| Immunogen Region: | 1-130 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human RBFOX1 (NP_665900.1). |
| Immunogen Sequence: | MLASQGVLLHPYGVPMIVPA APYLPGLIQGNQEAAAAPDT MAQPYASAQFAPPQNGIPAE YTAPHPHPAPEYTGQTTVPE HTLNLYPPAQTHSEQSPADT SAQTVSGTATQTDDAAPTDG QPQTQPSENT |
| Tissue Specificity | Predominantly expressed in muscle and brain. |
| Function | RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. |
| Protein Name | Rna Binding Protein Fox-1 Homolog 1Ataxin-2-Binding Protein 1Fox-1 Homolog AHexaribonucleotide-Binding Protein 1 |
| Database Links | Reactome: R-HSA-9022707 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Rna Binding Protein Fox-1 Homolog 1 antibodyAnti-Ataxin-2-Binding Protein 1 antibodyAnti-Fox-1 Homolog A antibodyAnti-Hexaribonucleotide-Binding Protein 1 antibodyAnti-RBFOX1 antibodyAnti-A2BP antibodyAnti-A2BP1 antibodyAnti-FOX1 antibodyAnti-HRNBP1 antibody |
Information sourced from Uniprot.org