| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RBBP9 |
| Gene ID: | 10741 |
| Uniprot ID: | RBBP9_HUMAN |
| Immunogen Region: | 1-186 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-186 of human RBBP9 (NP_006597.2). |
| Immunogen Sequence: | MASPSKAVIVPGNGGGDVTT HGWYGWVKKELEKIPGFQCL AKNMPDPITARESIWLPFME TELHCDEKTIIIGHSSGAIA AMRYAETHRVYAIVLVSAYT SDLGDENERASGYFTRPWQW EKIKANCPYIVQFGSTDDPF LPWKEQQEVADRLETKLHKF TDCGHFQNTEFHELITVVKS LLKVPA |
| Tissue Specificity | Expressed at higher levels in tumor tissues such as carcinoma. |
| Function | Serine hydrolase whose substrates have not been identified yet. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1. |
| Protein Name | Serine Hydrolase Rbbp9B5t-Overexpressed Gene ProteinProtein BogRetinoblastoma-Binding Protein 10Rbbp-10Retinoblastoma-Binding Protein 9Rbbp-9 |
| Alternative Antibody Names | Anti-Serine Hydrolase Rbbp9 antibodyAnti-B5t-Overexpressed Gene Protein antibodyAnti-Protein Bog antibodyAnti-Retinoblastoma-Binding Protein 10 antibodyAnti-Rbbp-10 antibodyAnti-Retinoblastoma-Binding Protein 9 antibodyAnti-Rbbp-9 antibodyAnti-RBBP9 antibodyAnti-BOG antibodyAnti-RBBP10 antibody |
Information sourced from Uniprot.org