Anti-RBBP5 IP antibody [SAA0256] (STJA0018771)

SKU:
STJA0018771
£378.50 - £1,632.50
Free Shipping
Processing The item has been added

Host: Mouse
Applications: ELISA/IF/IP
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Retinoblastoma-Binding Protein 5 is suitable for use in ELISA, Immunofluorescence and Immunoprecipitation research applications.
Clonality : Monoclonal
Clone ID : SAA0256
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: RBBP5
Gene ID: 5929
Uniprot ID: RBBP5_HUMAN
Function In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid. Does not affect ES cell self-renewal. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. In association with ASH2L and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B.
Protein Name Retinoblastoma-Binding Protein 5
Rbbp-5
Retinoblastoma-Binding Protein Rbq-3
Database Links Reactome: R-HSA-201722
Reactome: R-HSA-3214841
Reactome: R-HSA-3769402
Reactome: R-HSA-5617472
Reactome: R-HSA-8936459
Reactome: R-HSA-8951664
Reactome: R-HSA-9772755
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Retinoblastoma-Binding Protein 5 antibody
Anti-Rbbp-5 antibody
Anti-Retinoblastoma-Binding Protein Rbq-3 antibody
Anti-RBBP5 antibody
Anti-RBQ3 antibody

Information sourced from Uniprot.org