Anti-RASEF antibody (1-120) [S4211RM] (STJ11104211)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Ras And Ef-Hand Domain-Containing Protein (1-120) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4211RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RASEF |
| Gene ID | 158158 |
| Uniprot ID | RASEF_HUMAN |
| Immunogen Region | 1-120 |
| Immunogen Sequence | MEADGDGEELARLRSVFAAC DANRSGRLEREEFRALCTEL RVRPADAEAVFQRLDADRDG AITFQEFARGFLGSLRGGRR RDWGPLDPAPAVSEAGPETH DSEEDEGDEDAAAALATSCG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human RAB45 (NP_689786.2). |
Additional Info
| Tissue Specificity | Down-regulated in cutaneous melanoma cells but not in breast cancer cells. |
| Function | Binds predominantly GDP, and also GTP. Acts as a dynein adapter protein that activates dynein-mediated transport and dynein-dynactin motility on microtubules. |
| Protein Name | Ras And Ef-Hand Domain-Containing ProteinRas-Related Protein Rab-45 |
| Database Links | |
| Cellular Localisation | CytoplasmPerinuclear Region |
| Alternative Antibody Names | Anti-Ras And Ef-Hand Domain-Containing Protein antibodyAnti-Ras-Related Protein Rab-45 antibodyAnti-RASEF antibodyAnti-RAB45 antibody |
Information sourced from Uniprot.org