| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4211RM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RASEF |
| Gene ID: | 158158 |
| Uniprot ID: | RASEF_HUMAN |
| Immunogen Region: | 1-120 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human RAB45 (NP_689786.2). |
| Immunogen Sequence: | MEADGDGEELARLRSVFAAC DANRSGRLEREEFRALCTEL RVRPADAEAVFQRLDADRDG AITFQEFARGFLGSLRGGRR RDWGPLDPAPAVSEAGPETH DSEEDEGDEDAAAALATSCG |
| Tissue Specificity | Down-regulated in cutaneous melanoma cells but not in breast cancer cells. |
| Function | Binds predominantly GDP, and also GTP. Acts as a dynein adapter protein that activates dynein-mediated transport and dynein-dynactin motility on microtubules. |
| Protein Name | Ras And Ef-Hand Domain-Containing ProteinRas-Related Protein Rab-45 |
| Cellular Localisation | CytoplasmPerinuclear Region |
| Alternative Antibody Names | Anti-Ras And Ef-Hand Domain-Containing Protein antibodyAnti-Ras-Related Protein Rab-45 antibodyAnti-RASEF antibodyAnti-RAB45 antibody |
Information sourced from Uniprot.org