| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Ran guanine nucleotide release factor is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RANGRF |
| Gene ID: |
29098 |
| Uniprot ID: |
MOG1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of RANGRF at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human RANGRF |
| Function | May regulate the intracellular trafficking of RAN. Promotes guanine nucleotide release from RAN and inhibits binding of new GTP by preventing the binding of the RAN guanine nucleotide exchange factor RCC1. Regulates the levels of GTP-bound RAN in the nucleus, and thereby plays a role in the regulation of RAN-dependent mitotic spindle dynamics. Enhances the expression of SCN5A at the cell membrane in cardiomyocytes. |
| Protein Name | Ran Guanine Nucleotide Release FactorRangnrfRan-Binding Protein Mog1 |
| Database Links | Reactome: R-HSA-5576892 |
| Cellular Localisation | NucleusCytoplasmPerinuclear RegionCell MembranePeripheral Membrane ProteinCytoplasmic SideMay Shuttle Between The Nucleus And Cytoplasm |
| Alternative Antibody Names | Anti-Ran Guanine Nucleotide Release Factor antibodyAnti-Rangnrf antibodyAnti-Ran-Binding Protein Mog1 antibodyAnti-RANGRF antibodyAnti-MOG1 antibodyAnti-RANGNRF antibodyAnti-HSPC165 antibodyAnti-HSPC236 antibodyAnti-MDS5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
