| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RALGPS1 (1-300) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RALGPS1 |
| Gene ID: |
9649 |
| Uniprot ID: |
RGPS1_HUMAN |
| Immunogen Region: |
1-300 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RALGPS1 (NP_055451.1). |
| Immunogen Sequence: |
MYKRNGLMASVLVTSATPQG SSSSDSLEGQSCDYASKSYD AVVFDVLKVTPEEFASQITL MDIPVFKAIQPEELASCGWS KKEKHSLAPNVVAFTRRFNQ VSFWVVREILTAQTLKIRAE ILSHFVKIAKKLLELNNLHS LMSVVSALQSAPIFRLTKTW ALLNRKDKTTFEKLDYLMSK EDNYKRTREYIRSLKMVPSI PYLGIYLLDLIYIDSAYPAS GSIMENEQRSNQMNNILRI |
| Tissue Specificity | Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, pancreas, skeletal muscle, small intestine and thymus. |
| Function | Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization. Guanine nucleotide exchange factor for. |
| Protein Name | Ras-Specific Guanine Nucleotide-Releasing Factor Ralgps1Ral Gef With Ph Domain And Sh3-Binding Motif 1Ral Guanine Nucleotide Exchange Factor 2Ralgef 2Rala Exchange Factor Ralgps1 |
| Cellular Localisation | CytoplasmCell MembraneAssociates With Membranes Through The Ph Domain |
| Alternative Antibody Names | Anti-Ras-Specific Guanine Nucleotide-Releasing Factor Ralgps1 antibodyAnti-Ral Gef With Ph Domain And Sh3-Binding Motif 1 antibodyAnti-Ral Guanine Nucleotide Exchange Factor 2 antibodyAnti-Ralgef 2 antibodyAnti-Rala Exchange Factor Ralgps1 antibodyAnti-RALGPS1 antibodyAnti-KIAA0351 antibodyAnti-RALGEF2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
