| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Rad52 (125-418) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RAD52 |
| Gene ID: |
5893 |
| Uniprot ID: |
RAD52_HUMAN |
| Immunogen Region: |
125-418 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 125-418 of human Rad52 (NP_602296.2). |
| Immunogen Sequence: |
GYGVSEGLKSKALSLEKARK EAVTDGLKRALRSFGNALGN CILDKDYLRSLNKLPRQLPL EVDLTKAKRQDLEPSVEEAR YNSCRPNMALGHPQLQQVTS PSRPSHAVIPADQDCSSRSL SSSAVESEATHQRKLRQKQL QQQFRERMEKQQVRVSTPSA EKSEAAPPAPPVTHSTPVTV SEPLLEKDFLAGVTQELIKT LEDNSEKWAVTPDAGDGVVK PSSRADPAQTSDTLALNNQ |
| Post Translational Modifications | Phosphorylated upon DNA damage by ABL1, and probably by ATM or ATR. |
| Function | Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase. |
| Protein Name | Dna Repair Protein Rad52 Homolog |
| Database Links | Reactome: R-HSA-3108214Reactome: R-HSA-5685938Reactome: R-HSA-5685939 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna Repair Protein Rad52 Homolog antibodyAnti-RAD52 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
