Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-RAB6A (1-200) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
RAB6A |
Gene ID: |
5870 |
Uniprot ID: |
RAB6A_HUMAN |
Immunogen Region: |
1-200 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human RAB6A (NP_002860.2). |
Immunogen Sequence: |
MSTGGDFGNPLRKFKLVFLG EQSVGKTSLITRFMYDSFDN TYQATIGIDFLSKTMYLEDR TIRLQLWDTAGQERFRSLIP SYIRDSAAAVVVYDITNVNS FQQTTKWIDDVRTERGSDVI IMLVGNKTDLADKRQVSIEE GERKAKELNVMFIETSAKAG YNVKQLFRRVAAALPGMEST QDRSREDMIDIKLEKPQEQP |
Tissue Specificity | Ubiquitous. |
Post Translational Modifications | Prenylated. |
Function | Regulator of COPI-independent retrograde transport from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity. Recruits VPS13B to the Golgi membrane. Plays a role in neuron projection development (Probable). |
Protein Name | Ras-Related Protein Rab-6aRab-6 |
Database Links | Reactome: R-HSA-1912420Reactome: R-HSA-6798695Reactome: R-HSA-6811436Reactome: R-HSA-6811440Reactome: R-HSA-8854214Reactome: R-HSA-8873719Reactome: R-HSA-8876198 |
Cellular Localisation | Golgi Apparatus MembraneLipid-AnchorCytoplasmic VesicleSecretory VesicleAcrosome MembranePeripheral Membrane ProteinBicd2 Facilitates Its Targeting To Golgi Apparatus MembraneIsoform 1: Golgi Apparatus MembraneIsoform 2: Golgi Apparatus Membrane |
Alternative Antibody Names | Anti-Ras-Related Protein Rab-6a antibodyAnti-Rab-6 antibodyAnti-RAB6A antibodyAnti-RAB6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance