| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAB6A |
| Gene ID: | 5870 |
| Uniprot ID: | RAB6A_HUMAN |
| Immunogen Region: | 1-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human RAB6A (NP_002860.2). |
| Immunogen Sequence: | MSTGGDFGNPLRKFKLVFLG EQSVGKTSLITRFMYDSFDN TYQATIGIDFLSKTMYLEDR TIRLQLWDTAGQERFRSLIP SYIRDSAAAVVVYDITNVNS FQQTTKWIDDVRTERGSDVI IMLVGNKTDLADKRQVSIEE GERKAKELNVMFIETSAKAG YNVKQLFRRVAAALPGMEST QDRSREDMIDIKLEKPQEQP |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Prenylated. |
| Function | Regulator of COPI-independent retrograde transport from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity. Recruits VPS13B to the Golgi membrane. Plays a role in neuron projection development (Probable). |
| Protein Name | Ras-Related Protein Rab-6aRab-6 |
| Database Links | Reactome: R-HSA-1912420Reactome: R-HSA-6798695Reactome: R-HSA-6811436Reactome: R-HSA-6811440Reactome: R-HSA-8854214Reactome: R-HSA-8873719Reactome: R-HSA-8876198 |
| Cellular Localisation | Golgi Apparatus MembraneLipid-AnchorCytoplasmic VesicleSecretory VesicleAcrosome MembranePeripheral Membrane ProteinBicd2 Facilitates Its Targeting To Golgi Apparatus MembraneIsoform 1: Golgi Apparatus MembraneIsoform 2: Golgi Apparatus Membrane |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-6a antibodyAnti-Rab-6 antibodyAnti-RAB6A antibodyAnti-RAB6 antibody |
Information sourced from Uniprot.org
