| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RAB3D (1-219) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RAB3D |
| Gene ID: |
9545 |
| Uniprot ID: |
RAB3D_HUMAN |
| Immunogen Region: |
1-219 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-219 of human RAB3D (NP_004274.1). |
| Immunogen Sequence: |
MASAGDTQAGPRDAADQNFD YMFKLLLIGNSSVGKTSFLF RYADDSFTPAFVSTVGIDFK VKTVYRHDKRIKLQIWDTAG QERYRTITTAYYRGAMGFLL MYDIANQESFAAVQDWATQI KTYSWDNAQVILVGNKCDLE DERVVPAEDGRRLADDLGFE FFEASAKENINVKQVFERLV DVICEKMNESLEPSSSSGSN GKGPAVGDAPAPQPSSCSC |
| Tissue Specificity | Highly expressed in granulocytes of peripheral blood. Constitutively expressed at low levels in all hematopoietic cell lines investigated. |
| Post Translational Modifications | Phosphorylation of Thr-86 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM and CHML. |
| Function | Protein transport. Probably involved in regulated exocytosis. |
| Protein Name | Ras-Related Protein Rab-3d |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-8873719 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic Side |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-3d antibodyAnti-RAB3D antibodyAnti-GOV antibodyAnti-RAB16 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
