| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAB33A |
| Gene ID: | 9363 |
| Uniprot ID: | RB33A_HUMAN |
| Immunogen Region: | 118-237 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 118-237 of human RAB33A (NP_004785.1). |
| Immunogen Sequence: | DVTKMTSFTNLKMWIQECNG HAVPPLVPKVLVGNKCDLRE QIQVPSNLALKFADAHNMLL FETSAKDPKESQNVESIFMC LACRLKAQKSLLYRDAERQQ GKVQKLEFPQEANSKTSCPC |
| Tissue Specificity | Expressed only in lymphoid cell lines. |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Modulates autophagosome formation through interaction with ATG16L1. |
| Protein Name | Ras-Related Protein Rab-33aSmall Gtp-Binding Protein S10 |
| Database Links | Reactome: R-HSA-8854214Reactome: R-HSA-8873719 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic Side |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-33a antibodyAnti-Small Gtp-Binding Protein S10 antibodyAnti-RAB33A antibodyAnti-RABS10 antibody |
Information sourced from Uniprot.org
