| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ras-related protein Rab-32 (160-240 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAB32 |
| Gene ID: | 10981 |
| Uniprot ID: | RAB32_HUMAN |
| Immunogen Region: | 160-240 aa |
| Specificity: | RAB32 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 160-240 |
| Function | Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays an important role in the control of melanin production and melanosome biogenesis. In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes. Stimulates phosphorylation of RAB10 'Thr-73' by LRRK2. |
| Protein Name | Ras-Related Protein Rab-32 |
| Database Links | Reactome: R-HSA-8873719 Reactome: R-HSA-8876198 |
| Cellular Localisation | Mitochondrion Mitochondrion Outer Membrane Lipid-Anchor Cytoplasmic Vesicle Phagosome Phagosome Membrane Cytoplasmic Side Melanosome Melanosome Membrane Recruited To Phagosomes Containing S Aureus Or M Tuberculosis The Bloc-3 Complex A Heterodimer Of Hps1 And Hps4 Promotes Its Membrane Localization |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-32 antibody Anti-RAB32 antibody |
Information sourced from Uniprot.org