Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-RAB32 antibody (160-240 aa) (STJ191280)

SKU:
STJ191280
£48.00 - £252.00
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Ras-related protein Rab-32 (160-240 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RAB32
Gene ID: 10981
Uniprot ID: RAB32_HUMAN
Immunogen Region: 160-240 aa
Specificity: RAB32 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 160-240
Function Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays an important role in the control of melanin production and melanosome biogenesis. In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes. Stimulates phosphorylation of RAB10 'Thr-73' by LRRK2.
Protein Name Ras-Related Protein Rab-32
Database Links Reactome: R-HSA-8873719
Reactome: R-HSA-8876198
Cellular Localisation Mitochondrion
Mitochondrion Outer Membrane
Lipid-Anchor
Cytoplasmic Vesicle
Phagosome
Phagosome Membrane
Cytoplasmic Side
Melanosome
Melanosome Membrane
Recruited To Phagosomes Containing S
Aureus Or M
Tuberculosis
The Bloc-3 Complex
A Heterodimer Of Hps1 And Hps4 Promotes Its Membrane Localization
Alternative Antibody Names Anti-Ras-Related Protein Rab-32 antibody
Anti-RAB32 antibody

Information sourced from Uniprot.org

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