• Anti-Rab27b antibody at 1:500 dilution; lysates at 100 µg per lane; rabbit polyclonal to goat IgG (HRP) at 1:10000 dilution
  • Anti-Rab27b antibody Immunohistochemistry staining of mammary tissue; immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval; antibody concentration 1:200

Anti-RAB27B antibody (120aa C-Term) (STJ140078)

SKU:
STJ140078

£100.50 - £393.50
Current Stock:
Host: Goat
Applications: WB/IHC-F/IHC-P/IF
Reactivity: Human/Rat/Mouse/Monkey/Canine
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-RAB27B, member RAS oncogene family (120aa C-Term) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS, 20% Glycerol and 0.05% Sodium Azide.
Purification: This antibody is epitope-affinity purified from goat antiserum.
Concentration: 3 mg/ml
Dilution Range: WB 1:250-1:2000
IF 1:50-1:250
IHC-P 1:100-1:400
IHC-F 1:100-1:400
Storage Instruction: For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
Gene Symbol: RAB27B
Gene ID: 5874
Uniprot ID: RB27B_HUMAN
Immunogen Region: 120aa C-Term
Accession Number: ENSG00000041353
Specificity: Detects Rab27b by Western blot in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab27b. This antibody is specific for Rab27b. It does not recognize Rab27a protein.
Immunogen: Purified recombinant peptide derived from within residues 120 aa to the C-terminus of mouse Rab27b produced in E. coli.
Tissue Specificity Expressed primarily in testis.
Function Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1. May be involved in targeting uroplakins to urothelial apical membranes.
Protein Name Ras-Related Protein Rab-27b
C25kg
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-8873719
Reactome: R-HSA-8876198
Cellular Localisation Membrane
Lipid-Anchor
Late Endosome
Alternative Antibody Names Anti-Ras-Related Protein Rab-27b antibody
Anti-C25kg antibody
Anti-RAB27B antibody

Information sourced from Uniprot.org

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