• Western blot analysis of lysates from MCF-7, HUVEC, A549, and COLO cells, using RAB11FIP2 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from HepG2 cells using RAB11FIP2 antibody.
  • Western blot analysis of MCF-7 cells using Rab11-FIP2 Polyclonal Antibody

Anti-RAB11FIP2 antibody (340-389 aa) (STJ95308)

SKU:
STJ95308

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Rab11 family-interacting protein 2 (340-389 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RAB11FIP2
Gene ID: 22841
Uniprot ID: RFIP2_HUMAN
Immunogen Region: 340-389 aa
Specificity: Rab11-FIP2 Polyclonal Antibody detects endogenous levels of Rab11-FIP2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human RAB11FIP2 at the amino acid range 340-389
Function A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. Plays an essential role in phagocytosis through a mechanism involving TICAM2, RAC1 and CDC42 Rho GTPases for controlling actin-dynamics.
Protein Name Rab11 Family-Interacting Protein 2
Rab11-Fip2
Nrip11
Database Links Reactome: R-HSA-432040
Cellular Localisation Cell Projection
Phagocytic Cup
Cell Membrane
Peripheral Membrane Protein
Recycling Endosome Membrane
Translocates With Rab11a From The Vesicles Of The Endocytic Recycling Compartment (Erc) To The Plasma Membrane
Alternative Antibody Names Anti-Rab11 Family-Interacting Protein 2 antibody
Anti-Rab11-Fip2 antibody
Anti-Nrip11 antibody
Anti-RAB11FIP2 antibody
Anti-KIAA0941 antibody

Information sourced from Uniprot.org

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