• Immunofluorescence analysis of MCF-7 cells using QPCT antibody (STJ28794). Blue: DAPI for nuclear staining.
  • Western blot analysis of various lysates, using QPCT Rabbit polyclonal antibody (STJ28794) at 1:2500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-QPCT antibody (1-361) (STJ28794)

SKU:
STJ28794

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-QPCT (1-361) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:100
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: QPCT
Gene ID: 25797
Uniprot ID: QPCT_HUMAN
Immunogen Region: 1-361
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-361 of human QPCT (NP_036545.1).
Immunogen Sequence: MAGGRHRRVVGTLHLLLLVA ALPWASRGVSPSASAWPEEK NYHQPAILNSSALRQIAEGT SISEMWQNDLQPLLIERYPG SPGSYAARQHIMQRIQRLQA DWVLEIDTFLSQTPYGYRSF SNIISTLNPTAKRHLVLACH YDSKYFSHWNNRVFVGATDS AVPCAMMLELARALDKKLLS LKTVSDSKPDLSLQLIFFDG EEAFLHWSPQDSLYGSRHLA AKMASTPHPPGARGTSQLH
Function Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides Glu-3-amyloid-beta. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.
Protein Name Glutaminyl-Peptide Cyclotransferase
Glutaminyl Cyclase
Qc
Sqc
Glutaminyl-Trna Cyclotransferase
Glutamyl Cyclase
Ec
Database Links Reactome: R-HSA-6798695
Cellular Localisation Secreted
Alternative Antibody Names Anti-Glutaminyl-Peptide Cyclotransferase antibody
Anti-Glutaminyl Cyclase antibody
Anti-Qc antibody
Anti-Sqc antibody
Anti-Glutaminyl-Trna Cyclotransferase antibody
Anti-Glutamyl Cyclase antibody
Anti-Ec antibody
Anti-QPCT antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance