Anti-PYCR2 antibody (271-320) (STJ117349)

Name: Anti-PYCR2 antibody (271-320) (STJ117349)
SKU: STJ117349
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ117349

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Short Description	Rabbit polyclonal PYCR2 (271-320) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	PYCR2
Gene ID	29920
Uniprot ID	P5CR2_HUMAN
Immunogen Region	271-320
Immunogen Sequence	MADQEKISPAALKKTLLDRV KLESPTVSTLTPSSPGKLLT RSLALGGKKD
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 271-320 of human PYCR2 (NP_037460.2).

Tissue Specificity	Detected in erythrocytes (at protein level). Expressed in fetal brain.
Function	Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in cellular response to oxidative stress. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+).
Protein Name	Pyrroline-5-Carboxylate Reductase 2 P5c Reductase 2 P5cr 2
Database Links	Reactome: R-HSA-8964539
Cellular Localisation	Cytoplasm Mitochondrion
Alternative Antibody Names	Anti-Pyrroline-5-Carboxylate Reductase 2 antibody Anti-P5c Reductase 2 antibody Anti-P5cr 2 antibody Anti-PYCR2 antibody

Information sourced from Uniprot.org