| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Pseudouridylate synthase 1 homolog synthase is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PUS1 |
| Gene ID: |
80324 |
| Uniprot ID: |
PUS1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of PUS1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human PUS1 |
| Function | Pseudouridylate synthase that catalyzes pseudouridylation of tRNAs and mRNAs. Acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3'. Acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions. Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing. Involved in regulation of nuclear receptor activity through pseudouridylation of SRA1 mRNA. |
| Protein Name | Pseudouridylate Synthase 1 HomologTrna Pseudouridine Synthase 1Trna Pseudouridine(38-40 SynthaseTrna Pseudouridylate Synthase ITrna-Uridine Isomerase I |
| Database Links | Reactome: R-HSA-6782315 Q9Y606-2Reactome: R-HSA-6787450 Q9Y606-1 |
| Cellular Localisation | Isoform 1: MitochondrionIsoform 2: NucleusCytoplasm |
| Alternative Antibody Names | Anti-Pseudouridylate Synthase 1 Homolog antibodyAnti-Trna Pseudouridine Synthase 1 antibodyAnti-Trna Pseudouridine(38-40 Synthase antibodyAnti-Trna Pseudouridylate Synthase I antibodyAnti-Trna-Uridine Isomerase I antibodyAnti-PUS1 antibodyAnti-PP8985 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
