| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PTRH1 (1-214) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PTRH1 |
| Gene ID: |
138428 |
| Uniprot ID: |
PTH_HUMAN |
| Immunogen Region: |
1-214 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-214 of human PTRH1 (NP_001002913.1). |
| Immunogen Sequence: |
MRPGGFLGAGQRLSRAMSRC VLEPRPPGKRWMVAGLGNPG LPGTRHSVGMAVLGQLARRL GVAESWTRDRHCAADLALAP LGDAQLVLLRPRRLMNANGR SVARAAELFGLTAEEVYLVH DELDKPLGRLALKLGGSARG HNGVRSCISCLNSNAMPRLR VGIGRPAHPEAVQAHVLGCF SPAEQELLPLLLDRATDLIL DHIRERSQGPSLGP |
| Function | Peptidyl-tRNA hydrolase that cleaves nascent chains-tRNAs that are not stably fixed in the P-site of 60S ribosome-nascent chain complexes. Acts downstream of the ribosome-associated quality control (RQC) pathway to release non-ubiquitinated nascent chains from 60S and 80S ribosome-nascent chain complexes. Does not act on ubiquitinated nascent chains, which are cleaved by ANKZF1 for degradation. |
| Protein Name | Peptidyl-Trna HydrolasePth |
| Alternative Antibody Names | Anti-Peptidyl-Trna Hydrolase antibodyAnti-Pth antibodyAnti-PTRH1 antibodyAnti-C9orf115 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
