Anti-PTRH1 antibody (1-214) (STJ116658)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PTRH1 (1-214) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PTRH1 |
| Gene ID | 138428 |
| Uniprot ID | PTH_HUMAN |
| Immunogen Region | 1-214 |
| Immunogen Sequence | MRPGGFLGAGQRLSRAMSRC VLEPRPPGKRWMVAGLGNPG LPGTRHSVGMAVLGQLARRL GVAESWTRDRHCAADLALAP LGDAQLVLLRPRRLMNANGR SVARAAELFGLTAEEVYLVH DELDKPLGRLALKLGGSARG HNGVRSCISCLNSNAMPRLR VGIGRPAHPEAVQAHVLGCF SPAEQELLPLLLDRATDLIL DHIRERSQGPSLGP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-214 of human PTRH1 (NP_001002913.1). |
Additional Info
| Function | Peptidyl-tRNA hydrolase that cleaves nascent chains-tRNAs that are not stably fixed in the P-site of 60S ribosome-nascent chain complexes. Acts downstream of the ribosome-associated quality control (RQC) pathway to release non-ubiquitinated nascent chains from 60S and 80S ribosome-nascent chain complexes. Does not act on ubiquitinated nascent chains, which are cleaved by ANKZF1 for degradation. |
| Protein Name | Peptidyl-Trna HydrolasePth |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Peptidyl-Trna Hydrolase antibodyAnti-Pth antibodyAnti-PTRH1 antibodyAnti-C9orf115 antibody |
Information sourced from Uniprot.org