• Immunofluorescence analysis of C6 cells using PTP4A2 Rabbit polyclonal antibody (STJ117530) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunohistochemistry analysis of PTP4A2 in paraffin-embedded mouse lung using PTP4A2 Rabbit polyclonal antibody (STJ117530) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of PTP4A2 in paraffin-embedded human colon using PTP4A2 Rabbit polyclonal antibody (STJ117530) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of PTP4A2 in paraffin-embedded rat kidney using PTP4A2 Rabbit polyclonal antibody (STJ117530) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of various lysates using PTP4A2 Rabbit polyclonal antibody (STJ117530) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-PTP4A2 antibody (30-100) (STJ117530)

SKU:
STJ117530

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PTP4A2 (30-100) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
IHC-P 1:50-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTP4A2
Gene ID: 8073
Uniprot ID: TP4A2_HUMAN
Immunogen Region: 30-100
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human PTP4A2 (NP_536316.1).
Immunogen Sequence: FTEELKKYGVTTLVRVCDAT YDKAPVEKEGIHVLDWPFDD GAPPPNQIVDDWLNLLKTKF REEPGCCVAVH
Tissue Specificity Ubiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue.
Post Translational Modifications Farnesylated. Farnesylation is required for membrane targeting and for interaction with RABGGTB. Unfarnesylated forms are redirected to the nucleus and cytosol.
Function Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB.
Protein Name Protein Tyrosine Phosphatase Type Iva 2
Hu-Pp-1
Ov-1
Ptp(Caaxii
Protein-Tyrosine Phosphatase 4a2
Protein-Tyrosine Phosphatase Of Regenerating Liver 2
Prl-2
Database Links Reactome: R-HSA-8873719
Cellular Localisation Cell Membrane
Early Endosome
Cytoplasm
Alternative Antibody Names Anti-Protein Tyrosine Phosphatase Type Iva 2 antibody
Anti-Hu-Pp-1 antibody
Anti-Ov-1 antibody
Anti-Ptp(Caaxii antibody
Anti-Protein-Tyrosine Phosphatase 4a2 antibody
Anti-Protein-Tyrosine Phosphatase Of Regenerating Liver 2 antibody
Anti-Prl-2 antibody
Anti-PTP4A2 antibody
Anti-PRL2 antibody
Anti-PTPCAAX2 antibody
Anti-BM-008 antibody

Information sourced from Uniprot.org

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