• Immunohistochemistry analysis of paraffin-embedded lung cancer tissues with DAB staining using CCK-4 monoclonal antibody.
  • Western blot analysis using CCK-4 monoclonal antibody against HeLa (1) , A431 (2) , HCT116 (3) , Caco2 (4) , HepG2 (5) and MCF-7 (6) cell lysate.

Anti-PTK7 antibody [4F9] (STJ97900)

SKU:
STJ97900

£139.00 - £336.00
Current Stock:
Host: Mouse
Applications: WB/IHC/IF/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Inactive tyrosine-protein kinase 7 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Monoclonal
Clone ID: 4F9
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC 1:200-1:1000
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTK7
Gene ID: 5754
Uniprot ID: PTK7_HUMAN
Specificity: CCK-4 Monoclonal Antibody detects endogenous levels of CCK-4 protein.
Immunogen: Purified recombinant fragment of human CCK-4 expressed in E. Coli.
Post Translational Modifications MMP14 cleaves PTK7 between Pro-621 and Leu-622 generating an N-terminal soluble (70 kDa) fragment and a membrane C-terminal (50 kDa) fragment. Proteolysis by MMP14 regulates PTK7 function in non-canonical Wnt signaling pathway.
Function Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
Protein Name Inactive Tyrosine-Protein Kinase 7
Colon Carcinoma Kinase 4
Cck-4
Protein-Tyrosine Kinase 7
Pseudo Tyrosine Kinase Receptor 7
Tyrosine-Protein Kinase-Like 7
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Colocalizes With Mmp14 At Cell Junctions
Also Localizes At The Leading Edge Of Migrating Cells
Alternative Antibody Names Anti-Inactive Tyrosine-Protein Kinase 7 antibody
Anti-Colon Carcinoma Kinase 4 antibody
Anti-Cck-4 antibody
Anti-Protein-Tyrosine Kinase 7 antibody
Anti-Pseudo Tyrosine Kinase Receptor 7 antibody
Anti-Tyrosine-Protein Kinase-Like 7 antibody
Anti-PTK7 antibody
Anti-CCK4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance