| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PTGIR |
| Gene ID: | 5739 |
| Uniprot ID: | PI2R_HUMAN |
| Immunogen Region: | 207-386 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 207-386 of human PTGIR (NP_000951.1). |
| Immunogen Sequence: | TLSLCRMYRQQKRHQGSLGP RPRTGEDEVDHLILLALMTV VMAVCSLPLTIRCFTQAVAP DSSSEMGDLLAFRFYAFNPI LDPWVFILFRKAVFQRLKLW VCCLCLGPAHGDSQTPLSQL ASGRRDPRAPSAPVGKEGSC VPLSAWGEGQVEPLPPTQQS SGSAVGTSSKAEASVACSLC |
| Post Translational Modifications | Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C. |
| Function | Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase. |
| Protein Name | Prostacyclin ReceptorProstaglandin I2 ReceptorPgi ReceptorPgi2 ReceptorProstanoid Ip Receptor |
| Database Links | Reactome: R-HSA-391908Reactome: R-HSA-392851Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Prostacyclin Receptor antibodyAnti-Prostaglandin I2 Receptor antibodyAnti-Pgi Receptor antibodyAnti-Pgi2 Receptor antibodyAnti-Prostanoid Ip Receptor antibodyAnti-PTGIR antibodyAnti-PRIPR antibody |
Information sourced from Uniprot.org