• Immunofluorescence analysis of A549 cells, using PTGDR Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from HepG2 cells, using PTGDR Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of 293 cells using PD2R Polyclonal Antibody diluted at 1：1000

Anti-PTGDR antibody (263-312 aa) (STJ94989)

SKU:
STJ94989

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Prostaglandin D2 receptor (263-312 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTGDR
Gene ID: 5729
Uniprot ID: PD2R_HUMAN
Immunogen Region: 263-312 aa
Specificity: PD2R Polyclonal Antibody detects endogenous levels of PD2R protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human PTGDR at the amino acid range 263-312
Function Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate. Involved in PLA2G3-dependent maturation of mast cells. PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR.
Protein Name Prostaglandin D2 Receptor
Pgd Receptor
Pgd2 Receptor
Prostanoid Dp Receptor
Database Links Reactome: R-HSA-391908
Reactome: R-HSA-418555
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Prostaglandin D2 Receptor antibody
Anti-Pgd Receptor antibody
Anti-Pgd2 Receptor antibody
Anti-Prostanoid Dp Receptor antibody
Anti-PTGDR antibody

Information sourced from Uniprot.org

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