Name: Anti-PRSS8 antibody (C-Term) (STJ118847)
SKU: STJ118847
Availability: InStock

Anti-PRSS8 antibody (C-Term) (STJ118847)

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STJ118847

£112.50 - £524.50

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Host:	Rabbit
Applications:	WB/IF/ICC/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality :	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification:	Affinity purification
Concentration:	Lot specific
Dilution Range:	WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	PRSS8
Gene ID:	5652
Uniprot ID:	PRSS8_HUMAN
Immunogen Region:	C-Term
Specificity:	A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human PRSS8 (NP_002764.1).
Immunogen Sequence:	TCNCLYNIDAKPEEPHFVQE DMVCAGYVEGGKDACQGDSG GPLSCPVEGLWYLTGIVSWG DACGARNRPGVYTLASSYAS WIQSKVTELQPRVVPQTQES QPDSNLCGSHLAFSSAPAQG LLRPILFLPLGLALGLLSPW LSEH

Tissue Specificity	Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid.
Function	Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).
Protein Name	Prostasin Channel-Activating Protease 1 Cap1 Serine Protease 8 Cleaved Into - Prostasin Light Chain - Prostasin Heavy Chain
Database Links	Reactome: R-HSA-6809371
Cellular Localisation	Prostasin: Cell Membrane Single-Pass Membrane Protein Prostasin Light Chain: Secreted Extracellular Space Found In The Seminal Fluid Secreted After Cleavage Of Its C-Terminus Prostasin Heavy Chain: Secreted
Alternative Antibody Names	Anti-Prostasin antibody Anti-Channel-Activating Protease 1 antibody Anti-Cap1 antibody Anti-Serine Protease 8 Cleaved Into - Prostasin Light Chain - Prostasin Heavy Chain antibody Anti-PRSS8 antibody

Information sourced from Uniprot.org

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STJ110205	Anti-FLNA antibody (C-Term) (STJ110205)	Rabbit	Polyclonal	Human/Mouse/Rat	WB/IHC-P/ELISA

Anti-PRSS8 antibody (C-Term) (STJ118847)