• Immunofluorescence analysis of U-2 OS cells using PRSS8 Rabbit polyclonal antibody (STJ118847) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Western blot analysis of lysates from Mouse kidney, using PRSS8 Rabbit polyclonal antibody (STJ118847) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-PRSS8 antibody (C-Term) (STJ118847)

SKU:
STJ118847

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PRSS8 (C-Term) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PRSS8
Gene ID: 5652
Uniprot ID: PRSS8_HUMAN
Immunogen Region: C-Term
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human PRSS8 (NP_002764.1).
Immunogen Sequence: TCNCLYNIDAKPEEPHFVQE DMVCAGYVEGGKDACQGDSG GPLSCPVEGLWYLTGIVSWG DACGARNRPGVYTLASSYAS WIQSKVTELQPRVVPQTQES QPDSNLCGSHLAFSSAPAQG LLRPILFLPLGLALGLLSPW LSEH
Tissue Specificity Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid.
Function Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).
Protein Name Prostasin
Channel-Activating Protease 1
Cap1
Serine Protease 8 Cleaved Into - Prostasin Light Chain - Prostasin Heavy Chain
Database Links Reactome: R-HSA-6809371
Cellular Localisation Prostasin: Cell Membrane
Single-Pass Membrane Protein
Prostasin Light Chain: Secreted
Extracellular Space
Found In The Seminal Fluid
Secreted After Cleavage Of Its C-Terminus
Prostasin Heavy Chain: Secreted
Alternative Antibody Names Anti-Prostasin antibody
Anti-Channel-Activating Protease 1 antibody
Anti-Cap1 antibody
Anti-Serine Protease 8 Cleaved Into - Prostasin Light Chain - Prostasin Heavy Chain antibody
Anti-PRSS8 antibody

Information sourced from Uniprot.org

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