• Western blot analysis of lysates from HepG2 cells, using Peripherin Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of HepG2 cells using PRPH Polyclonal Antibody diluted at 1：1000
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Peripherin Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using PRPH Polyclonal Antibody diluted at 1：1000

Anti-PRPH antibody (421-470 aa) (STJ95235)

SKU:
STJ95235

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Peripherin (421-470 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PRPH
Gene ID: 5630
Uniprot ID: PERI_HUMAN
Immunogen Region: 421-470 aa
Specificity: PRPH Polyclonal Antibody detects endogenous levels of PRPH protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Peripherin at the amino acid range 421-470
Post Translational Modifications Phosphorylated.phosphorylation increases after nerve injury in regenerating neurons.
Function Class-III neuronal intermediate filament protein. May form an independent structural network without the involvement of other neurofilaments or may cooperate with the neuronal intermediate filament proteins NEFL, NEFH, NEFM and INA to form a filamentous network. Assembly of the neuronal intermediate filaments may be regulated by RAB7A. Plays a role in the development of unmyelinated sensory neurons. May be involved in axon elongation and axon regeneration after injury. Inhibits neurite extension in type II spiral ganglion neurons in the cochlea.
Protein Name Peripherin
Neurofilament 4
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Projection
Axon
Perikaryon
Alternative Antibody Names Anti-Peripherin antibody
Anti-Neurofilament 4 antibody
Anti-PRPH antibody
Anti-NEF4 antibody
Anti-PRPH1 antibody

Information sourced from Uniprot.org

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