Anti-PRPF3 antibody (STJA0007332)

SKU:
STJA0007332

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-U4/U6 small nuclear ribonucleoprotein Prp3 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PRPF3
Gene ID: 9129
Uniprot ID: PRPF3_HUMAN
Specificity: This antibody detects endogenous levels of PRPF3 at Human, Mouse
Immunogen: Synthesized peptide derived from human PRPF3
Post Translational Modifications Ubiquitinated. Undergoes 'Lys-63'-linked polyubiquitination by PRPF19 and deubiquitination by USP4. 'Lys-63'-linked ubiquitination increases the affinity for PRPF8 and may regulate the assembly of the U4/U6-U5 tri-snRNP complex.
Function Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
Protein Name U4/U6 Small Nuclear Ribonucleoprotein Prp3
Pre-Mrna-Splicing Factor 3
Hprp3
U4/U6 Snrnp 90 Kda Protein
Database Links Reactome: R-HSA-72163
Cellular Localisation Nucleus
Nucleus Speckle
Alternative Antibody Names Anti-U4/U6 Small Nuclear Ribonucleoprotein Prp3 antibody
Anti-Pre-Mrna-Splicing Factor 3 antibody
Anti-Hprp3 antibody
Anti-U4/U6 Snrnp 90 Kda Protein antibody
Anti-PRPF3 antibody
Anti-HPRP3 antibody
Anti-PRP3 antibody

Information sourced from Uniprot.org

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