| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PROZ |
| Gene ID: | 8858 |
| Uniprot ID: | PROZ_HUMAN |
| Immunogen Region: | 220-340 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-340 of human PROZ (NP_003882.1). |
| Immunogen Sequence: | SLLHRNITVKTYFNRTSQDP LMIKITHVHVHMRYDADAGE NDLSLLELEWPIQCPGAGLP VCTPEKDFAEHLLIPRTRGL LSGWARNGTDLGNSLTTRPV TLVEGEECGQVLNVTVTTRT Y |
| Tissue Specificity | Plasma. |
| Post Translational Modifications | The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. |
| Function | Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids. |
| Protein Name | Vitamin K-Dependent Protein Z |
| Database Links | Reactome: R-HSA-159740Reactome: R-HSA-159763Reactome: R-HSA-159782 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Vitamin K-Dependent Protein Z antibodyAnti-PROZ antibody |
Information sourced from Uniprot.org
